What is malic acid converted to in biological processes?

In biological processes, malic acid is primarily converted to oxaloacetic acid, especially within the context of the citric acid cycle (Krebs cycle). This transformation is significant because oxaloacetic acid plays a crucial role in metabolic pathways, facilitating energy production through the Krebs cycle.

During this conversion, malic acid, which is an intermediate in the cycle, undergoes an oxidation reaction facilitated by the enzyme malate dehydrogenase. This process generates oxaloacetate while reducing NAD+ to NADH, which is essential for cellular respiration. Oxaloacetic acid then participates in various metabolic reactions, including replenishing the cycle and forming citrate when combined with acetyl-CoA.

Understanding this conversion highlights the interconnectedness of metabolic pathways and the importance of intermediates like malic acid in energy production and biosynthesis within cells.